August 7, 2026

Drs. Westerhoff and Kakar Lead New Edition of Diagnostic Pathology: Hepatobiliary and Pancreas

Dr. Maria Westerhoff, alongside Co-Lead Author Dr. Sanjay Kakar of the University of California, San Francisco, has captured the latest advancements in gastrointestinal pathology in the newly published fourth edition of Diagnostic Pathology: Hepatobiliary and Pancreas. Published by Elsevier, the full-color textbook is now available as a comprehensive, expertly curated guide to one of the most challenging areas in pathology.

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August 5, 2026

Cancer Cell Study Identifies Promising New Therapeutic Strategy for Aggressive Neuroendocrine Prostate Cancer

Researchers at the University of Michigan have identified a previously unrecognized survival mechanism in neuroendocrine prostate cancer (NEPC), one of the most aggressive and difficult-to-treat forms of prostate cancer. The findings, which have been published in Cancer Cell, uncover a critical vulnerability in NEPC and suggest a novel dual-targeting strategy that could eventually lead to more effective treatment options for patients with advanced disease.

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July 10, 2026

Cyclosporiasis Cases Increase in Southeast Michigan: Testing Guidance for MLabs Clinicians

The Michigan Department of Health and Human Services (MDHHS) and local health departments are investigating a recent increase in cyclosporiasis cases, primarily affecting Southeast Michigan counties along the Ohio border. Cyclosporiasis cases typically increase during the summer months; however, the current increase is above expected seasonal incidence. Investigations are underway to identify a potential common exposure or source.

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June 17, 2026

David Manthei, MD, PhD, Named Associate Clinical Pathology Director

By Lynn McCain When Dr. David Manthei talks about his work, one theme comes up again and again: connection. Whether he is bringing together laboratory teams, mentoring residents, or collaborating with clinicians across disciplines, his focus is on strengthening relationships that ultimately improve patient care. Named Associate Director of the Clinical Pathology Division on March 1, 2026, Manthei brings a broad perspective shaped by his many roles. He serves as Section Director of Immunology and Special Chemistry, Associate Program Director for the Pathology Residency Program, Program Director

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May 13, 2026

Where Chemistry Meets Biology: Dr. Amol Mhetre’s Work in Translational Pathology

By Lynn McCain From a young age in India, Amol Mhetre, PhD, was fascinated by organic chemistry, not just as a subject but as a way to understand how molecules behave in real biological systems and to develop new therapeutics to treat disease. That curiosity has carried him across continents and into a career at the interface of chemistry, biology, and translational drug discovery. In March 2026, Mhetre was promoted to Research Investigator in the University of Michigan Department of Pathology, where his work focuses on the design and synthesis of novel small‑molecule inhibitors with

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April 8, 2026

Michigan Researchers Uncover How a 'Frankenstein' Gene Fuels Aggressive Childhood Cancer

By Anastazia Hartman Researchers in the Parolia Lab at the University of Michigan have uncovered how a single genetic event can make Ewing sarcoma—a rare and aggressive bone and soft tissue cancer that primarily affects children and young adults—more dangerous. Their findings reveal that when a gene called STAG2 is lost, the core cancer-driving protein EWS-FLI1 is redirected toward powerful genetic “on switches” that dramatically boost tumor-promoting genes. Ewing sarcomas arise from a genetic accident causing a fusion between two independent genes, EWSR1 and FLI1. When parts of these genes

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April 7, 2026

From Health Lab: Researchers identify new therapeutic target for neuroendocrine tumors in the gastrointestinal tract

By Anastazia Hartman Researchers identify new therapeutic target for neuroendocrine tumors in the gastrointestinal tract Targeting two separate pathways that control lipid synthesis led to longer survival in mouse models By Ananya Sen Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. They're scattered throughout the body, including the stomach, intestines, pancreas and lungs. Tumors that arise from these cells are called neuroendocrine tumors and are often rare and slow growing. Around 70% of all neuroendocrine tumors arise in the pancreas or

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