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We offer 1800+ tests in clinical, molecular and anatomic pathology.

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NEWS & EVENTS

Twelve Pathology Faculty Promotions Approved

On May 21, 2026, the University of Michigan Board of Regents approved promotions for 12 Department of Pathology Faculty. Their new appointments take effect September 1, 2026.

Dr. Sara Varadarajan: Finding Balance at the Cellular Frontier

When Dr. Sara Varadarajan stepped into her new faculty role on April 1, it marked a professional milestone in her scientific journey. Her path has been shaped by curiosity, resilience, and a deep commitment to understanding how tissues heal and restore balance after injury. Most recently, Varadarajan received a prestigious NIH K99/R00 Pathway to Independence Award from the National Institute of Allergy and Infectious Diseases (NIAID).

Where Chemistry Meets Biology: Dr. Amol Mhetre’s Work in Translational Pathology

By Lynn McCain

 

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Featured Test

 

FGFR Mutation/Translocation


Erdafitinib (Balversa™) is an FGFR-inhibitor that is FDA-approved for the treatment of metastatic urothelial cancers harboring susceptible mutations or translocations involving FGFR2 or FGFR3. 
 

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NCRC Staff

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Myeloid NGS Panel

This test is intended for the molecular evaluation of myeloid neoplasms including myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms, acute myeloid leukemias (AML), mastocytosis and myeloid neoplasms with eosinophilia and gene rearrangement.


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TFE3 Rearrangement (FISH)

 Detecting rearrangements involving the TFE3 gene region (Xp11.2) via fluorescence in situ hybridization (FISH) to qualitatively assess for the presence of TFE3 translocations that are associated with certain subtypes of renal cell carcinoma. Testing for TFE3 gene rearrangement may aid in the diagnosis and classification of renal tumors.


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NCRC Staff

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NGS Solid Tumor Panel


Molecular testing of solid tumor neoplasms - particularly advanced-stage cancer. This DNA and RNA based, NGS test targets 50 actionable genes (35 mutations, 19 amplifications, 21 - fusions). Requires <1mm2 of tissue (as little as 100 tumor cells) and a low 3% QNS rate. 

 

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PIK3CA Mutation: 

NEW TREATMENT OPTION FOR METASTATIC BREAST CANCER

MLabs offers NGS Solid Tumor Panel and Single gene test to detect PIK3CA for FDA approved therapy alpelisib (Piqray®).


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Featured Test

 

NR4A3 (9q22-9q31) Rearrangement (FISH)

NR4A3 encodes an orphan nuclear receptor. Rearrangements of NR4A3 occur in more than 80% of extraskeletal myxoid chondrosarcoma (EMC) as well as in salivary acinic cell carcinoma (AciCC), driving tumorigenesis. 


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