August 13, 2025

FDA Approves First-Ever Drug for a Rare and Aggressive Brain Cancer

Department of Pediatrics originally published in 2023 has lead the U.S. Food and Drug Administration (FDA) to accelerate approval of the drug ONC201 now called dordaviprone for the treatment of diffuse midline glioma (DMG) with an H3 K27M mutation. A rare, aggressive brain tumor that primarily affects children and young adults. This marks the first FDA-approved therapy for this form of cancer.

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June 4, 2025

The Path to Discovery

Jennifer Brazil, PhD, Assistant Professor of Pathology at Michigan Medicine began her own research laboratory in 2018. She continued to research the mechanisms by which polymorphonuclear neutrophils (PMN) and epithelial glycans can be targeted to alter neutrophil transepithelial migration and neutrophil function under conditions of intestinal inflammation and repair.

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June 3, 2025

Enhancing Heart Failure Patient Care with the MOS Dashboard

Heart failure with reduced ejection fraction (HFrEF), which measures your heart’s ability to pump oxygen-rich blood out to your body, remains a leading cause of death and hospitalization worldwide. Over the last three decades, clinical trials have highlighted the efficacy of four key medication classes- Beta-blockers, angiotensin-converting enzyme inhibitors (ACEis), angiotensin receptor-neprilysin inhibitors (ARNI), and sodium-glucose cotransporter 2 inhibitors (SGLT2i).

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May 5, 2025

The Art of Science

Like prisms spread light in a variety of hues, Dr. Yang Xiao’s talents spread across multiple disciplines, creating a spectrum of color in this world. Dr. Xiao is one of Pathology’s newest faculty members and was recruited as a tenure-track assistant professor. However, she is not only a member of Pathology but also holds joint appointments in Biomedical Engineering and Computational Medicine & Bioinformatics departments and is a member of the Bioscience Initiative Single-Cell Spatial Analysis Program (SCSAP).

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April 21, 2025

The Unseen Heroes of Healthcare

Pathology Laboratory Professionals Week is an annual celebration honoring the vital contributions of medical laboratory professionals to patient care and public health. This year, we celebrate from April 21 to 25, 2025.

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