Days Set Up
Monday - Friday, 8:00am - 4:00pm
Analytic Time

10-14 days

MiChart Code
TFE3 Rearrangement by FISH
Soft Order Code

Test Updated:


Renal Cell Carcinoma
TFE3 gene region Xp11.2

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Test Overview

Test Methodology

Fluorescence In Situ Hybridization (FISH)

Test Usage

This test detects rearrangements involving the TFE3 gene region (Xp11.2) via fluorescence in situ hybridization (FISH) in formalin-fixed, paraffin-embedded tissue specimens. FISH is performed using a dual-color break-apart probe (Empire Genomics) to qualitatively assess for the presence of TFE3 translocations that are associated with certain subtypes of renal cell carcinoma. Testing for TFE3 gene rearrangement may aid in the diagnosis and classification of renal tumors.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Submit a formalin-fixed, paraffin block of the renal tumor tissue (with matched benign renal tissue if available); store at room temperature.

Minimum Volume

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.