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We offer 1800+ tests in clinical, molecular and anatomic pathology.

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NEWS & EVENTS

Kamran Mirza, MD, PhD Receives PAPs Distinguished Service Award

We are pleased to announce that Kamran Mirza, MD, PhD, professor of pathology and assistant chair for pathology education, was awarded the Pakistani-American Pathologists’ Society’s Distinguished Service Award.

Expect the Unexpected: MEST Cases in the Male Reproductive Tract

One of the key qualities of expert pathologists is that they learn to expect the unexpected. In the Michigan Medicine Department of Pathology, our pathologists and collaborators recently reported on some of these unexpected findings.

Using Technology to Advance Patient Care and Safety

In decades past, people often lived lifelong within a narrow geographic region and received healthcare from one institution. Today, our population is highly mobile. Individuals may receive healthcare from locations across the United States and globally. This causes significant safety issues for patients who need blood transfusions, especially those who are unable to relay their medical history.

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Featured Test

 

FGFR Mutation/Translocation


Erdafitinib (Balversa™) is an FGFR-inhibitor that is FDA-approved for the treatment of metastatic urothelial cancers harboring susceptible mutations or translocations involving FGFR2 or FGFR3. 
 

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NCRC Staff

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Myeloid NGS Panel

This test is intended for the molecular evaluation of myeloid neoplasms including myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms, acute myeloid leukemias (AML), mastocytosis and myeloid neoplasms with eosinophilia and gene rearrangement.


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TFE3 Rearrangement (FISH)

 Detecting rearrangements involving the TFE3 gene region (Xp11.2) via fluorescence in situ hybridization (FISH) to qualitatively assess for the presence of TFE3 translocations that are associated with certain subtypes of renal cell carcinoma. Testing for TFE3 gene rearrangement may aid in the diagnosis and classification of renal tumors.


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NCRC Staff

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NGS Solid Tumor Panel


Molecular testing of solid tumor neoplasms - particularly advanced-stage cancer. This DNA and RNA based, NGS test targets 50 actionable genes (35 mutations, 19 amplifications, 21 - fusions). Requires <1mm2 of tissue (as little as 100 tumor cells) and a low 3% QNS rate. 

 

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PIK3CA Mutation: 

NEW TREATMENT OPTION FOR METASTATIC BREAST CANCER

MLabs offers NGS Solid Tumor Panel and Single gene test to detect PIK3CA for FDA approved therapy alpelisib (Piqray®).


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Featured Test

 

NR4A3 (9q22-9q31) Rearrangement (FISH)

NR4A3 encodes an orphan nuclear receptor. Rearrangements of NR4A3 occur in more than 80% of extraskeletal myxoid chondrosarcoma (EMC) as well as in salivary acinic cell carcinoma (AciCC), driving tumorigenesis. 


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