Posted Date
Effective Date
Test Name Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum
Update Type Miscellaneous
CPT Code 86255 x12, 86341, 86053, 86363 
Order Code PCDES

TEST PANEL UPDATE

 

Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum

Order Code:                  PCDES

Fee Code:                     AA979, AA978, AA997, AA998 (CPT 86255 x11, 86341, 86053, 86363)

New CPT Codes:          86255 x12, 86341, 86053, 86363                       

Reference Laboratory:   Mayo PCDES

 

The following changes will be made to the Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum, assay performed by Mayo Clinic Laboratories effective October 13, 2026:

 

The following tests will be added to the panel:

  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Tissue Immunofluorescence, Serum (GL5IS)
  • Gamma-Amino Butyric Acid Type A (GABA-A) Receptor Antibody, Cell-Binding Assay, Serum (GBACS)

 

The following test will be removed from the panel:

  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Immunofluorescence, Serum (GFAIS)

 

The following tests will be added to the reflex algorithm:

  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Cell Based Assay, Serum (GL5CS)
  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Tissue Immunofluorescence Titer, Serum (GL5TS)

 

The following tests will be removed from the reflex algorithm:

  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Cell Binding Assay, Serum (GFACS) 
  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Immunofluorescence Titer Assay, Serum  (GFATS) 

 

 

 

 

 

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