Posted Date
Effective Date
Update Type New Tests
CPT Code 88184 x2, 88185 x6
Order Code PNHRW

NEW TEST

 

Paroxysmal Nocturnal Hemoglobinuria (PNH) Profile

Order Code:                  PNHRW

Fee Code:                     21582, 21583, 23041 x6 (CPT 88184 x2, 88185 x6)

 

 

MLabs will begin offering a Paroxysmal Nocturnal Hemoglobinuria (PNH) Profile test effective September 10, 2025. This test replaces the PNH Marker Panel (order code PLINK) currently sent to Mayo Clinic Laboratories.

 

Collection Instructions: Collect a FULL tube of blood in a yellow top ACD A or B Vacutainer ® tube (minimum 1.0 mL). (EDTA is acceptable) Send intact specimen at room temperature within 12 hours of collection. DO NOT FREEZE. Specimen should arrive at the Flow Cytometry Laboratory within 72 hours of collection.  The following information is required on a Hematopathology Consult requisition:

  1. Relevant clinical history
  2. Clinical or morphological findings and suspicions
  3. Date and time of collection
  4. Phone number and after-hours pager number for ordering physician

     

Reference Range: RED BLOOD CELLS: PNH RBC-Partial Antigen Loss: 0.00 - 0.02%; PNH RBC-Complete Antigen Loss: 0.00 - 0.01%; PNH Granulocytes: 0.00 - 0.01%; PNH Monocytes: 0.00 – 0.1%

*Reference ranges may change over time. Please refer to the original patient report when evaluating results. *