Posted Date
Effective Date
Test Name Leptin
Update Type Test Methodology Changed
CPT Code 83520
Order Code FLEP
Referral Laboratory Mayo Medical Laboratories

EFFECTIVE DATE:    March 22, 2024   





Order Code:        FLEP

Fee Code:        AA082 (CPT 83520)

Reference Laboratory:    Mayo FLEP (Esoterix Endocrinology)


Effective March 22, 2024, the test methodology for the Leptin assay referred to Esoterix Endocrinology has changed from Enzyme Immunoassay (EIA) to Enzyme-Linked Immunosorbent Assay (ELISA). This change has resulted in updates to specimen collection and handling and reference ranges as follows:


Specimen Collection:  A fasting specimen is recommended (8-12 hour fast). Collect specimen in a red top or SST tube. Centrifuge and aliquot 1 mL of serum into a screw capped plastic vial within 45 minutes of collection. Freeze (preferred) or send at room temperature or refrigerated within 48 hours.


Reference Range: Adults (BMI=22): Male: 0.7 – 5.3 ng/mL, Female: 3.3 – 18.3 ng/mL. Please contact laboratory for other BMI reference ranges.