Posted Date
Effective Date
Test Name Multiple Sclerosis (MS) Profile, Serum and CSF
Update Type Reference range changed
Order Code MSP3

REFERENCE RANGE CHANGE

Multiple Sclerosis (MS) Profile, Serum and CSF

Order Code: MSP3

Fee Code: AA992

Reference Laboratory: Mayo MSP3

The test algorithm and reference ranges for Mayo Clinic Laboratories Multiple Sclerosis Profile have been updated as follows effective August 30, 2022, to clarify reflex decision points:

Kappa free light-chain testing will be performed by nephelometry on all samples. When kappa free light-chain testing indicates either borderline or positive results (> or =0.0600 mg/dL), the oligoclonal banding tests will be performed at an additional charge. If the time of testing exceeds the specimen stability for oligoclonal banding tests, only kappa free light-chain testing will be performed. Kappa free light-chain testing will only be performed up to specimen stability.

Reference Range:

KAPPA FREE LIGHT CHAIN: Medical decision point: 0.1000 mg/dL, Positive: > or =0.1000 mg/dL, Borderline: 0.0600 mg/dL-0.0999 mg/dL, Negative: <0.0600 mg/dL.

OLIGOCLONAL BANDS: <2 bands

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