Test Overview
Test Methodology

KCSFP: Nephelometry
OLIGC, OLIGS: Isoelectric Focusing (IEF) with IgG Immunoblot Detection

Test Usage

Diagnosing multiple sclerosis, especially helpful in patients with equivocal clinical or radiological findings

Reference Range *

Kapp Free Light Chains: Medical decision point: 0.1000 mg/dL
Oligoclonal bands: <2 bands

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

4 - 6 days

Soft Order Code
MSP3
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo MSP3
    Section
    Special Testing
    Specimen Requirements
    Collection

    Collect serum in an SST or red top tube. Spin and aliquot within 2 hours of collection, into a screw capped plastic tube. Label the aliquot as serum. Send to Specimen Processing frozen.
    Collect CSF in a screw capped plastic tube. Label as CSF, and send to Specimen Processing frozen.

    Special Handling

    Serum and CSF must be collected within 7 days of each other

    Normal Volume
    Serum: 1 mL; CSF: 1 mL
    Minimum Volume
    Serum: 0.5 mL; CSF: 0.5 mL
    Storage Temperature
    Frozen preferred; Refrigerated- CSF only good 72 hours, serum is 14 days
    Additional Information

    Kappa free light chain will be performed by nephelometry on all samples. When kappa free light chain results are 0.0600 mg/dL or more, the oligoclonal banding tests will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test performed by Mayo Clinic Laboratories

    Billing
    CPT Code
    83521
    Fee Code
    AA992
    NY State Approved
    No