OLIGC, OLIGS: Isoelectric Focusing (IEF) with IgG Immunoblot Detection
Diagnosing multiple sclerosis, especially helpful in patients with equivocal clinical or radiological findings
Kapp Free Light Chains: Medical decision point: 0.1000 mg/dL
Oligoclonal bands: <2 bands
4 - 6 days
Collect serum in an SST or red top tube. Spin and aliquot within 2 hours of collection, into a screw capped plastic tube. Label the aliquot as serum. Send to Specimen Processing frozen.
Collect CSF in a screw capped plastic tube. Label as CSF, and send to Specimen Processing frozen.
Serum and CSF must be collected within 7 days of each other
Kappa free light chain will be performed by nephelometry on all samples. When kappa free light chain results are 0.0600 mg/dL or more, the oligoclonal banding tests will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test performed by Mayo Clinic Laboratories