21 - 28 days
WFS1 Gene Sequencing
WFS1 Mutation Analysis
Sensorineural Deafness Testing
Autosomal Dominant Non-Syndromic Sensorineural Deafness Testing
WFS1 Gene Sequencing Shadow
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The coding exons and associated, adjacent consensus splice sites of the WFS1 gene are amplified using specific primers, and bidirectionally sequenced using a fluorescent method.
Analysis of the presence of WFS1 mutations in sensorineural deafness patients, confirmation of a diagnosis of Wolfram Syndrome, and carrier testing in families with a know WFS1 mutation.
Interpretive report provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimen in a lavender top tube. Send intact specimen within 24 hours if stored at room temperature or within 5 days if stored refrigerated. Include the patient's family history, pedigree, and ethnicity on the test requisition. Obtaining informed consent from the patient prior to genetic testing is strongly recommended. If desired, a UMHS Request and Consent for Genetic Testing form can be obtained from the MMGL Molecular Genetics Laboratory by contacting the MLabs Client Services Center at 800-862-7284 or online at https://mlabs.umich.edu/sites/default/files/2020-01/file/pci-mmgl_infor….