Test Overview
Test Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Test Usage
Monitoring peak levels of voriconazole, especially in individuals with reduced liver function, individuals with CYP2C19 polymorphisms associated with poor metabolic funtion, or individuals taking medications that affect CYP2C19 activity.
Reference Range *
1.0 - 5.5 mcg/mL
Test Limitations
Voriconazole metabolism may be altered by coadministration of drugs that metabolically induce or inhibit CYP2C19 or by genetic polymorphisms that affect enzyme activity.
Test Details
Days Set Up
Monday - Sunday
Analytic Time
2 - 3 days
Soft Order Code
VORI
MiChart Code
Voriconazole Level
Synonyms
- Voriconazole Level
- VORI
- VFEND
Laboratory
Sendout
Reference Laboratory
Mayo VORI (88698)
Section
Special Testing
Specimen Requirements
Collection Instructions
Collect specimen in a red top tube; do not use SST tube. Centrifuge within 2 hours of draw, aliquot serum into a plastic vial and refrigerate.
Normal Volume
2 mL serum
Minimum Volume
0.6 mL serum
Rejection Criteria
SST tube not acceptable.
Additional Information
Test sent to Mayo Clinic Laboratories.
Billing
CPT Code
80285
Fee Code
AA694
NY State Approved
No