Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Monitoring peak levels of voriconazole, especially in individuals with reduced liver function, individuals with CYP2C19 polymorphisms associated with poor metabolic funtion, or individuals taking medications that affect CYP2C19 activity.
1.0 - 5.5 mcg/mL
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Voriconazole metabolism may be altered by coadministration of drugs that metabolically induce or inhibit CYP2C19 or by genetic polymorphisms that affect enzyme activity.
2 - 3 days
- Voriconazole Level
Collect specimen in a red top tube; do not use SST tube. Centrifuge within 2 hours of draw, aliquot serum into a plastic vial and refrigerate.
Test sent to Mayo Clinic Laboratories.