Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Monitoring peak levels of voriconazole, especially in individuals with reduced liver function, individuals with CYP2C19 polymorphisms associated with poor metabolic funtion, or individuals taking medications that affect CYP2C19 activity.

Reference Range *

1.0 - 5.5 mcg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Voriconazole metabolism may be altered by coadministration of drugs that metabolically induce or inhibit CYP2C19 or by genetic polymorphisms that affect enzyme activity.

Test Details
Days Set Up
Monday - Sunday
Analytic Time

2 - 3 days

Soft Order Code
MiChart Code
Voriconazole Level
  • Voriconazole Level
  • VORI
Reference Laboratory
Mayo VORI (88698)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube; do not use SST tube. Centrifuge within 2 hours of draw, aliquot serum into a plastic vial and refrigerate.

Normal Volume
2 mL serum
Minimum Volume
0.6 mL serum
Storage Temperature
Refrigerated preferred, ambient or frozen acceptable
Rejection Criteria
SST tube not acceptable.
Additional Information

Test sent to Mayo Clinic Laboratories.

CPT Code
Fee Code