Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Assessment of thiamin deficiency. Thiamin measurement is appropriate in patients with behavioral changes, eye signs, gait disturbances, delirium, and encephalopathy; or in patients with questionable nutritional status, especially those who appear at risk and who also are being given insulin for hyperglycemia.

Reference Range *

70 - 180 nmol/L

Test Limitations

Vitamin supplementation and nonfasting specimens may result in elevated thiamine diphosphate concentrations.

Test Details
Days Set Up
Monday - Friday
Analytic Time

2 - 6 days

Soft Order Code
TDP
MiChart Code
Vitamin B1, Whole Blood
Synonyms
  • Thiamin (Vitamin B1), WB
  • B1, Whole Blood
  • B1
  • Thiamine, Whole Blood
  • Thiamine
  • TDP
  • Vitamin
Laboratory
Sendout
Reference Laboratory
Mayo TDP (85753)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a lavender top tube (EDTA) following an overnight (12 hour) fast. Invert 8-10 times to mix blood, pour whole blood into an plastic vial, and freeze. Protect specimen from light.DO NOT SPIN

Special Handling

Fasting specimen. Protect specimen from light. Aliquot (pour) whole blood to amber PFL tube before freezing.DO NOT SPIN

Rejection Criteria
Specimen not protected from light. Not frozen as whole blood in amber PFL tube.
Specimen received as plasma at Mayo. DO NOT SPIN
Normal Volume
4 mL whole blood
Minimum Volume
0.5 mL whole blood
Storage Temperature
Strict frozen
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
84425
Fee Code
22110
LOINC
2998-3
NY State Approved
No