Update Type: New Tests
Test Updated: 02/09/2022
Test Overview
Test Methodology

Fluorescence Enzyme Immunoassay (FEIA)

Test Usage

Assessing possible mast cell activation, which may occur as a result of anaphylaxis, allergen challenge, or mast cell activation syndrome. Assessing possible systemic mastocytosis, with increased number of mast cells.

Reference Range *

<11.5 ng/mL

Test Limitations

Tryptase levels might not be elevated in patients with acute mast cell activation if specimen is obtained >12 hours after anaphylaxis.

Test Details
Days Set Up
Twice weekly. Tuesdays and Thursdays.
Soft Order Code
TRYP
MiChart Code
Tryptase, Serum
Laboratory
Chemical Pathology
Section
Special Chemistry
Specimen Requirements
Collection Instructions

Collect in an SST or red top tube. Centrifuge and transfer serum into plastic aliquot tube. Freeze aliquot (refrigeration acceptable).

Alternate Specimen
Red top serum.
Normal Volume
0.5 mL serum
Minimum Volume
0.2 mL serum
Storage Temperature
Refrigerated at 2 - 8 °C, stable 7 days.
Freeze at -20 °C for longer storage.
Billing
CPT Code
83520
Fee Code
KA051
LOINC
21582-2
NY State Approved
No