Test Overview

Test Methodology

Mass Spectrometry

Test Usage

Diagnosis of Trimethylaminuria.

Reference Range*

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Soft Order Code




Trimethylamine (TMA) and TMA N-oxide (TMAO) (Quantitative)

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Laboratory Reference

Mayo Wild 246 (ZW246) (Children's Hospital Colorado L6949)

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Specimen Requirements

Normal Volume

5 mL aliquot from random urine

Minimum Volume

1 mL aliquot from random urine

Additional Information

Trimethylaminuria is a presumably genetic defect in the enzymatic conversion of trimethylamine (odor of stale fish) to trimethylamine-N-oxide (non-odiferous). Diagnosis is made by detection of excess trimethylamine in urine. Available treatments include dietary restrictions of choline and foods containing trimethylamine inhibitors. Test sent to Mayo Medical Laboratories; performed by Children's Hospital Colorado.

Billing Information

Fee Codes

CPT Code

83789, 82570

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