Test Overview
Test Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Test Usage

Measurement of topiramate serum concentration is useful for monitoring dosage compliance and to guide dose adjustment during co-therapy with phenytoin or carbamazepine.

Reference Range *

5.0 - 20.0 mcg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

8 hours

Soft Order Code
TOPRM
MiChart Code
Topiramate, Serum
Synonyms
  • TOPIR
  • Topiramate, Serum
  • Topamax
Laboratory
Chemical Pathology
Section
Drug Analysis
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Rejection Criteria
SST tube not acceptable.
Yellow Top Tube
Red Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.3 mL serum
Billing
CPT Code
80201
Fee Code
KA019
LOINC
17713-9
Resources