Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Therapeutic drug monitoring.
< 235 ng/mL
Peak concentrations and elimination half-life are affected by fat content in food, time of day and concomitant medications.
4 - 8 days
Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. For maximum clinical significance, usual sampling times are Peak: 1 hour after administration of oral dose or Trough: immediately before next dose is given. Indicate whether specimen is Peak, Trough, or Random level.
Test sent to Mayo Medical Laboratories; performed by MedTox Laboratories.