Test Overview
Test Methodology

Competitive assay with electrochemiluminescence detection

Test Usage

Measurement of Thyrotropin Receptor Antibody (TRAb) is used to diagnose and manage autoimmune thyroid disease (i.e., Graves disease), neonatal hypothyroidism, and postpartum thyroid dysfunction. The test is the recommended first-line test for detection of thyrotropin receptor antibodies and measures the presence of stimulating, blocking and neutral antibodies. Using a decision limit of 1.75 IU/L, the test has a sensitivity of 97% and a specificity of 99% for detection of Graves disease.

Reference Range *

0.00 - 1.75 IU/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

For diagnostic purposes, the results should always be assessed in combination with the patients medical history, clinical examination, and other findings.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

1 hour

Soft Order Code
TRAB
MiChart Code
TRAB
Synonyms
    Laboratory
    Clinical Core Laboratory
    Section
    Clinical Chemistry
    Specimen Requirements
    Collection

    Collect in Serum Separator Tube (SST), and spin. Stable for 7 hours at room temperature 20-25C, 6 days at 2-8C and 12 months at -20 C(freeze only once)

    Collection Instructions

    Collect in Serum Separate Tube (SST), spin and aliquot serum in a plastic vial.  Stable for 7 hours at room temperature 20-25C, 6 days at 2-8C and 12 months at -20C (freeze only once)

    Normal Volume

    1.0 mL

    Minimum Volume

    0.5 mL

    Storage Temperature
    Stable for 7 hours at 20-25°C, 6 days at 2-8°C and 12 months at -20°C (freeze only once)
    Billing
    CPT Code
    83520
    Fee Code
    JA051
    LOINC
    5385-0
    NY State Approved
    No