Thrombophilia Profile

Test Overview

Test Methodology

PTSC, APTSC, DRV1, TTSC, APCRV: Optical Clot-Based; CLFIB: Clauss; DIMER, PSF: Latex ; Immunoassay (LIA); ATTF, CFX: Chromogenic Assay; PTNT: Direct Mutation Analysis

Reference Range *

Interpretive report provided

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Patient should not be receiving coumadin (warfarin), heparin, direct thrombin inhibitors (argatroban, dabigatran) or direct factor Xa inhibitors (apixaban, rivaroxaban, and edoxaban).

Test Details

Days Set Up

Monday - Friday

Analytic Time

6 - 8 days

Soft Order Code

AATHR

Laboratory

Sendout

Reference Laboratory

Mayo AATHR

Section

Special Testing

Specimen Requirements

Collection

Collect whole blood in EDTA lavender top tube or ACD tube. Send to Specimen Processing at room temperature.
Plasma: Must be collected before factor replacement therapy. Centrifuge blue top tubes and aliquot plasma (1 mL each) into an aliquot tube. Centrifuge again, aliquotting into 5 tubes of 1 mL plasma each. Freeze plasma immediately, must be within 4 hours of collection..

Special Handling

Both whole blood and plasma are required

Alternate Specimen

ACD tube is acceptable in place of EDTA tube

Normal Volume

3 mL whole blood AND 5 mL (1 mL in each of 5 aliquot tubes) of platelet poor double spun plasma

Minimum Volume

1 mL whole blood AND 5 mL (1 mL in each of 5 aliquot tubes) of platelet poor double spun plasma

Storage Temperature

Whole blood= ambient; Double spun plasma= strict frozen

Additional Information

Test performed by Mayo Clinic Laboratories

Billing

CPT Code

81240, 85300, 85303, 85306, 85307, 85379, 85384, 85390, 85610, 85613, 85670, 85730