Test Overview
Test Usage
Phenotypic test that provides a quantitative measurement of TPMT enzyme activity levels to assist physicians with azathioprine (Imuran) or 6-MP (Purinethol) dosing strategies. Individuals with low thiopurine methyltransferase are at risk of excessive myelosuppression.
Reference Range *
Normal TPMT Activity: >21.0 EU/mL; Intermediate TPMT Activity: 6.0-21.0 EU/mL; Low TPMT Activity: <6.0 EU/mL.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Days Set Up
Monday - Friday
Analytic Time
5 - 8 days
Soft Order Code
TPMTE
MiChart Code
TPMT Enzyme, Erythrocytes
Synonyms
- Thiopurine Methyltransferase (TPMT), Phenotype
- TPMT Enzyme
- TPMTPHE
- TPMT Phenotype
- Thiopurine Methyltransferase (TPMT), Erythrocytes, Enzyme Activity
Laboratory
Sendout
Reference Laboratory
Prometheus 3320
Section
Special Testing
Specimen Requirements
Additional Information
Test sent to Prometheus Labs.
Billing
CPT Code
82657
Fee Code
36155