6MMP and 6TG
6 Thioguanine (6 TG)
6 Methyl Mercaptopurine (6 MMP)
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Used to individualize dosing and balance therapeutic response with possible toxicity for patients on thiopurine therapy. Provides measurement of 6-TG (correlated with clinical response and leukopenia) and 6-MMP (correlated with hepatotoxicity) metabolites. Metabolite testing shuld not replace laboratory monitoring for toxicity.
6-TGN: 235 - 400 pmole/8x10(8) RBC, 6-MMPN: <5700 pmole/8x10(8) RBC.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.