Test Overview
Test Methodology
HPLC
Test Usage
Used to individualize dosing and balance therapeutic response with possible toxicity for patients on thiopurine therapy. Provides measurement of 6-TG (correlated with clinical response and leukopenia) and 6-MMP (correlated with hepatotoxicity) metabolites. Metabolite testing shuld not replace laboratory monitoring for toxicity.
Reference Range *
6-TGN: 235 - 400 pmole/8x10(8) RBC, 6-MMPN: <5700 pmole/8x10(8) RBC.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Analytic Time
14 days
Soft Order Code
6MMP
MiChart Code
Thiopurine Metabolites, 6-TG and 6-MMP
Synonyms
- 6MMP and 6TG
- 6MMP
- 6 Thioguanine (6 TG)
- 6 Methyl Mercaptopurine (6 MMP)
- PRO-PredictRx Metabolites
- Thiopurine Metabolites
- Imuran Metabolites
Laboratory
Sendout
Reference Laboratory
Prometheus 3200
Section
Special Testing
Specimen Requirements
Collection Instructions
Collect specimen in a lavender top tube. Refrigerate and send intact specimen within 5 days of collection. Do not freeze.
Normal Volume
5 mL EDTA whole blood
Minimum Volume
3 mL EDTA whole blood
Additional Information
Test sent to Prometheus Labs.
Billing
CPT Code
82542
Fee Code
AA225