SYPNB: Multiplex Flow Immunoassay
RPRS, RRPRQ: Flocculation/Agglutination
RTPPA: Particle Agglutination
An aid in the diagnosis of active syphilis (Treponema pallidum) infection and routine prenatal screening.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Despite active syphilis, serologic tests may be negative in severely immunosuppressed patients such as those with AIDS. In very early cases of primary syphilis, serology tests for syphilis may be negative. In cases of untreated, late/latent syphilis, the result of RPR may be negative. However, the syphilis screening test (MFI) and TP-PA should be positive.
2 - 5 days
Collect specimen in an SST or Red top tube. Centrifuge, aliquot serum into plastic vial and freeze.
If the results for IgG are positive, a Rapid Plasma Reagin (RPR) assay will be performed automatically at an additional charge. If the RPR is positive, an RPR Titer will be performed at an additional charge. If the RPR is negative, Syphilis Antibody TP-PA will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories.