Test Overview
Test Methodology

Nontreponemal flocculation procedure (RPR).

Test Usage

Screening test for syphilis

Reference Range *

Nonreactive

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Nonspecific positive reactions may be found in SLE, malaria, infectious mononucleosis, hepatitis, leprosy, brucellosis, atypical pneumonia, typhus, and other infections. Reactive tests due to related treponemal infections (bejel, pinta, or yaws) may also occur. A reactive result in a newborn may be due to passive transfer from mother's blood.

Test Details
Days Set Up
Monday - Friday
Analytic Time

8 hours

Soft Order Code
RPR
Synonyms
  • Rapid Plasma Reagin
  • Rapid Plasma Reagin, Serum
  • RPR, Serum
  • Serologic Test for Syphilis
  • STS
  • Syphilis Antibody Screen
  • Syphilis Screening Test
  • Treponema pallidum Antibody Screen, Serum
  • VDRL Equivalent, Serum
  • Rapid Plasma Reagin
  • Serologic Test for Syphilis
  • STS
  • Syphilis Screening Test
  • VDRL Equivalent, Serum
  • RPR
  • RPRQN
  • RPR QUANT, SERUM
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into plastic vial and refrigerate.
Contaminated, lipemic or grossly hemolyzed sera should not be used because of the possibility of nonspecific reactions.

Alternate Specimen
Red top tube.
Plasma, EDTA, heparin or sodium citrate
Normal Volume
0.5 ml serum
Minimum Volume
0.5 ml serum
Rejection Criteria
CSF
Additional Information

Reactive specimens will be titered (RPRQN) and the more specific TPPA will be performed.

Billing
CPT Code
86592
Fee Code
21922
Reflex CPT
86593 Titer, 86780 TPPA
Reflex Fee Code
21923 RPRQN, KA050 TPPA
LOINC
20507-0 (RPR), 31147-2 (RPRQN)