Test Overview
Test Methodology

Particle agglutination

Test Usage

Aids in the diagnosis of syphilis by confirming presence of Treponema pallidum antibodies.

Reference Range *

Non-reactive

Test Limitations

TPPA may be reactive in persons from areas where yaws and pinta is or was endemic. Samples from patients with HIV, Leprosy, Toxoplasmosis, H. Pylori, and drug addiction may react with test particles causing false-positive or inconclusive results.

Test Details
Days Set Up
Tuesday, Friday
Analytic Time

8 hours

Soft Order Code
TPPA/TPRP
MiChart Code
Syphilis Antibody, Treponema pallidum Particle Agglutination, Serum
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into plastic vial and refrigerate. Store at 2-8C up to 5 days. Freeze serum for longer storage.

Normal Volume
1.5 mL serum
Minimum Volume
1.0 mL serum
Storage Temperature
2-8C
Rejection Criteria
Samples frozen and thawed more than once.
Additional Information

The identification of Treponema pallidum antibodies aids in the diagnosis of syphilis caused by the microorganisms belonging to the genus Treponema and provides epidemiological information on syphilis. A reactive treponemal test indicates past or present infection and usually remains positive for life. A non-reactive result indicates no past or present infection, but may occur during incubation-stage syphilis.

Billing
CPT Code
86780
Fee Code
KA050
LOINC
24312-1
NY State Approved
No