Synovasure PJI and NSA

Test Overview

Test Methodology

Immunoassay

Test Usage

Synovasure® Alpha Defensin test results are intended to be used in conjunction with other clinical and diagnostic findings to aid a patient’s diagnosis. Synovasure® Alpha Defensin is intended to determine whether there is an infection present in the synovial fluid of a joint. Results do not identify a specific type of infection or establish the origin or severity of an infection. Results provide a physician with a specific positive or negative indication for the presence of the alpha defensin biomarker that is released into the synovial fluid by the patient’s cells while fighting an infection.

Reference Range *

Alpha Defensin Negative
CRP < 3 mg/L for the PJI test and < 7.5 mg/L in the NSA test
Hemoglobin < 20 g/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Set Up

Monday - Friday

Analytic Time

2 - 5 days

Soft Order Code

SYNOS or SYNOP

MiChart Code

SYNOS/SYNOP

Synonyms

Alpha Defensins, Synovial Fluid

Laboratory

Sendout

Reference Laboratory

Citrano Diagnostic Labs

Section

Special Testing

Specimen Requirements

Collection Instructions

Collect aspirate from affected joint. Aspirate must must put into a plain red top tube. Send to Specimen Processing at ambient temperature. Please indicate if fluid was collected from a non-replacement joint (native) (SYNOS) or from a prosthetic joint (SYNOP).