Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent vaccines. Assessing the IgG antibody response to active immunization with conjugated, 13-valent vaccines. Determining the ability of an individual to produce an antibody response to polysaccharide antigen(s), as part of an evaluation for humoral or combined immunodeficiencies.
Result reported in mcg/mL; results greater than the reference value are consistent with a positive immune response.
The humoral immune response to S. pneumoniae is age dependent, and the database of IgG antibody concentrations to different serotypes is incomplete. The minimum concentration of IgG antibody necessary to ensure protection against invasive disease has not been determined for any serotype. Serotype specific antibodies may persist for up to 10 years following immunization or infection.
3 - 6 days
- Anti-Pneumococcal Antibodies
- Pneumococcal Antibody Titer, IgG
- Pneumococcal IgG Vaccine Response, ELISA
- Pneumo-Vax Response
- S. pneumoniae IgG Antibody
- S. pneumoniae IgG Ab, 7 Seroty
- S. pneumoniae IgG Ab,23 seroty
- PNEUMOCOCCAL IgG VAC RES ELISA
Collect blood in a red top or SST tube. Centrifuge, aliquot serum into plastic vial and refrigerate. Pre- and post-vaccination samples submitted at the same time are recommended. Post-vaccination samples should be collected 4-6 weeks from the date of vaccination.
Includes serotypes 1(1), 2(2), 3(3), 4(4), 5(5), 8(8), 9N(9), 12F(12), 14(14), 17F(17), 19F(19), 20(20), 22F(22), 23F(23), 6B(26), 10A(34), 11A(43), 7F(51), 15B(54), 18C(56), 19A(57), 9V(68), and 33F(70). Testing should be performed with pre- and post- vaccination sera. Test sent to Mayo Medical Laboratories.