The evaluation of suspected iron-deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status. It is also used in the evaluation of insulin-dependent diabetics for iron-deficiency resulting from gastric autoimmunity and atrophic gastritis.
1.8 - 4.6 mg/L
The SOTFR immunoassay should not be used for routine clinical evaluation of patients for iron status when ferritin immunoassay would be appropriate, such as in the absence of confounding pathologies (inflammation, chronic disease, or malignancy). Patients with hemodialysis and recent blood loss may have falsely elevated SOTFR levels. SOTFR is elevated in patients with thalassemia and sickle cell disease. Caution should be exercised in managing anemia in these individuals based on the SOTFR test results
Collect specimen in an SST or Red top tube. Centrifuge, aliquot serum into a plastic vial and freeze within 2 hours.