Test Overview
Test Methodology

High resolution typing (NGS) and Solid Phase Assay

Test Usage

HLA antibody screening is performed to detect and characterize antibodies directed against HLA antigens in patient serum. HLA typing is performed using next-generation sequencing (NGS) to identify the specific HLA alleles of patients. Together, these results are used to perform interpretation of virtual and physical crossmatches and guide optimal donor selection, reducing immunologic risk and improving transplant outcomes.

Test Details
Days Set Up
Monday - Friday, 7:00am - 4:00pm
Analytic Time

5 days

Soft Order Code
HLLRD, HLAS
Synonyms
  • HLA Antibody Screening
  • HLA Typing Class I and II
  • Percent Reactive Antibody (PRA)
  • New Patient, Solid Organ Tx
  • HLA Antibody Specificity Class II
  • HLA Class II Low Resolution
  • HLA Class I Low Resolution
  • HLA Antibody Specificity Class I
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection

Collect specimen in sufficient yellow top (ACD) solution A and sufficient red top/SST. Send specimen at room temperature. Do not refrigerate or freeze.

Normal Volume

HLLRD: Full tubes, 2- Yellow top (ACD) solution A tube
HLAS: Full tubes, 1 Red top/SST

Minimum Volume

HLLRD: Full tubes, 2- Yellow top (ACD) solution A tube
HLAS: Full tubes, 1 Red top/SST

Storage Temperature
Room temperature
Rejection Criteria
Frozen samples, mislabeled samples, samples that do not have the required two patient identifiers.
Billing
CPT Code
81370, 81376 x3, 86832, 86833
Fee Code
OA006, OA007 x3, 37962, 37963
NY State Approved
No