24 - 48 hours
SCID (Severe Combined Immunodeficiency Disorder)
Immunodeficiencies Profile, SCID
SCID Panel Shadow
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Evaluation of possible severe combined immunodeficiency. Testing is performed only on infants identified by State of Michigan TREC study as potential SCIDS patients. A full lymphoid cell panel is run, including B and T cell, T subsets, T-memory and naive subsets, and natural killer cell quantitation. Markers include:
Calculated CD4:CD8 ratio (T4:T8 ratio)
[link text="SCIDS reference range.docx" href="/static/apps/handbook/Tables/SCIDS reference range.docx"]
[bold]*Pediatric Reference Ranges from Journal of Allergy and Clinical Immunology, vol. 112, No. 5, 11/2003 and studies performed at Michigan Medicine Flow Cytometry Laboratory. Absolute ranges are calculated utilizing absolute lymphocyte count ranges for the same age groups provided by the hematology laboratory.[/bold]
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Testing performed only for University of Michigan registered patients.