Test Overview
Test Methodology

EIA

Test Usage

Anti-SAE 1 IgG autoantibody can be used to assist in the diagnoses and characterization of a subset of dermatomyositis (DM) patients. It is highly specific for DM (>95%) and is present in 5-8% of the European DM population. Initial disease onset may consist of mild myopathic features with severe skin involvement; however, extensive myalgia and muscle disease with weakness can appear as the disease progresses. It is associated with dysphagia and systemic symptoms (i.e. fevers, weight loss, increased inflammatory markers). In one cohort, an association with ILD and cancer had been found.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Analytic Time

10 days

Soft Order Code
LSAE
MiChart Code
Anti-SAE
Synonyms
  • Anti-SAE 1 IgG
Laboratory
Sendout
Reference Laboratory
Labcorp (Esoterix # 520011)
Section
Special Testing
Specimen Requirements
Collection

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Plasma is also acceptable (EDTA, heparin, or citrate).

Yellow Top Tube
Normal Volume
1 mL serum
Storage Temperature
Ambient: 24 hours ambient, Refrigerated: 7 days, Frozen: 2 months.
Additional Information

Test sent to Labcorp Dublin; performed by Esoterix Endocrinology

Billing
CPT Code
83520
Fee Code
AA301
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