Test Overview

Test Usage

Anti-SAE 1 IgG autoantibody can be used to assist in the diagnoses and characterization of a subset of dermatomyositis (DM) patients. It is highly specific for DM (>95%) and is present in 5-8% of the European DM population. Initial disease onset may consist of mild myopathic features with severe skin involvement; however, extensive myalgia and muscle disease with weakness can appear as the disease progresses. It is associated with dysphagia and systemic symptoms (i.e. fevers, weight loss, increased inflammatory markers). In one cohort, an association with ILD and cancer had been found.

Test Details

Analytic Time

10 days

Soft Order Code


MiChart Code




Anti-SAE 1 IgG

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Laboratory Reference

RDL Reference Laboratories 176

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Specimen Requirements


Yellow Top Tube

Normal Volume

1 mL serum

Additional Information

Test sent to RDL Reference Laboratories.

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