Test Overview
Test Methodology

Indirect Fluorescent Antibody (IFA)

Test Usage

Antigen-specific IgG and IgM titers allow rapid diagnosis of infection by organisms within either of the two major groups of Rickettsia. The spotted fever group includes R. rickettsia (Rocky Mountain Spotted Fever) and R. akari (Rickettsial pox). The typhus group includes R. typhi (endemic/maurine typhus) and R. prowazeki (epidemic typhus).

Reference Range *

Screen: Not detected. Titer: <1:64
R. typhi IgG, R. typhi IgM

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.

Test Details
Days Set Up
Tuesday, Thursday
Analytic Time

1 - 5 days

Soft Order Code
MiChart Code
  • Febrile Agglutinins
  • Rickettsia rickettsii
  • Weil-Felix Agglutinins
  • Rickettsia typhi
  • Murine Typhus
  • Rocky Mountain Spotted Fever
  • Typhus Fever Group Antibody
  • Spotted Fever Group Antibody
  • Febrile Antibodies Panel replacement (Rickettsia)
  • Tick Borne Disease
Reference Laboratory
Quest Valencia 37507
Special Testing
Specimen Requirements
Collection Instructions

Collect blood in a red top or SST tube. Centrifuge, aliquot serum into plastic vial and refrigerate. EDTA (lavender top), heparinized (green top) or ACD (yellow top) plasma is also acceptable.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Additional Information

Panel includes Rickettsia Spotted Fever and Rickettsia Typhus Fever IgG and IgM antibody screen. If IgG or IgM antibodies are detected the appropriate titer will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Quest Diagnostics Nichols Institute of Valencia. Test sent to Quest Diagnostics Nichols Institute of Valencia.

CPT Code
86757 x4
Reflex CPT
86757 per titer