Test Overview
Test Methodology

Immunofluorescence (IFA); Western Blot reflex if indicated

Test Usage

Anti-Ri can be detected in patients with the paraneoplastic opsoclonus / myoclonus syndrome. Neoplasms most often associated with Anti-Ri include breast cancer, gynecological cancers, and small cell lung cancer.

Reference Range *


* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

4 - 7 days

Soft Order Code
  • Sensory Neuropathy Antibody
  • ANNA-2
  • Antineuronal Nuclear Antibody (ANNA) Type 2
  • Paraneoplastic Autoantibody, Antineuronal Nuclear Antibody 2
  • Anti-Ri
  • Neuronal Nuclear Antibody, Type 2
Reference Laboratory
Quest Valencia 10140
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Normal Volume
0.5 mL serum
Minimum Volume
0.2 mL serum
Additional Information

If the Ri Antibody screen by IFA is positive, Ri Antibody by Western Blot will be performed at an additional charge. If the Ri Antibody by Western Blot is positive, Ri Antibody Titer will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Quest Diagnostics Nichols Institute of Valencia.

CPT Code
Reflex CPT
Western Blot: 84181, Titer: 86256.