Test Overview
Test Methodology

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Aiding in the biochemical diagnosis of Krabbe disease using whole blood specimens
Follow-up of individuals affected with Krabbe disease
Follow-up testing after an abnormal newborn screening result for Krabbe disease
Monitoring of individuals at risk to develop late onset Krabbe disease
Monitoring of individuals with Krabbe disease after hematopoietic stem cell transplantation

Reference Range *

Normal <5 pmol/g Hb

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Individuals with later onset disease, such as adult-onset Krabbe disease, may have a normal psychosine result.

Test Details
Days Set Up
Tuesday, Thursday
Analytic Time

4 - 8 days

Soft Order Code
PSYR
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo PSYR
    Section
    Special Testing
    Specimen Requirements
    Collection Instructions

    Collect specimen in an EDTA lav top tube. Send to Specimen Processing refrigerated.

    Special Handling

    MUST be sent refrigerated

    Alternate Specimen
    Green top (Lithium or sodium heparin)
    Normal Volume
    2 mL whole blood
    Minimum Volume
    0.5 mL whole blood
    Storage Temperature
    Strict refrigerate
    Rejection Criteria
    Specimen sent ambient or frozen
    Additional Information

    Test performed by Mayo Clinic Laboratories

    Billing
    CPT Code
    82542
    NY State Approved
    No