Days Set Up
Analytic Time

1 - 2 days

MiChart Code
Pseudocholinesterase (PCHE) Total (Sendout)
Soft Order Code

Test Updated:


Insecticide poisoning
Nerve gas poisoning

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Test Overview

Test Methodology

Photometric, Acetylthiocholine Substrate

Test Usage

Monitoring for exposure to organophosphorus insecticides. Monitoring patients with liver disease, particularly those undergoing liver transplantation. Identifying those patients with an atypical gene who have low levels of cholinesterase which is not inhibited by dibucaine. These individuals are sensitive to the muscle relaxant succinylcholine since they are unable to hydrolyze it rapidly.

Reference Range

Reference values have not been established for patients that are less than 18 years of age. Males: >or=18 yrs: 3,100 - 6,500 U/L; Females: 18-49 yrs: 1,800 - 6,600 U/L; >or=50 yrs: 2,550 - 6,800 U/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. For cases of prolonged apnea following surgery, wait 24 hours before obtaining specimen. SST tube must be spun within 2 hours of collection.

Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.