Test Overview
High-Pressure Liquid Chromatography (HPLC) with Fluorescence Detection
Establishing a biochemical diagnosis of erythropoietic protoporphyria and X-linked dominant protoporphyria.
Free Protoporphyrin: <20 mcg/dL packed cells; Zinc-Complexed Protoporphyrin: <60 mcg/dL packed cells.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
2 - 6 days
- Erythrocyte Protoporphrin
- Erythrocyte Protoporphyrins, Fractionation
- FEP
- FEP (Free Erythrocyte Protoporphyrins)
- Free Erythrocyte Protoporphyrins (FEP)
- Free Erythrocyte Protoporphyrins (FEP)
- Protoporphyrins, Fractionation, RBC
Specimen Requirements
Patient should abstain from alcohol for 24 hours and be off medications for 1 week prior to specimen collection. If it is clinically inappropriate to discontinue medications, forward a list of medications with the specimen. Collect blood in a green top tube from a fasting patient (12 - 14 hour fast). Place on wet ice immediately. Refrigerate and send intact whole blood specimen within 24 hours of collection.
Fasting specimen. Place on ice immediately.
Additional Information
Includes separate quantitation of zinc protoporphyrin and free protoporphyrin. Test sent to Mayo Medical Laboratories.