Test Overview

Test Methodology

Latex Immunoassay

Test Usage

Diagnosis of congenital or acquired protein S deficiency states.

Reference Range*

Males: Free 65 - 160%, Total 80 - 160%; Females, age <50 yrs: Free 50 - 160%, Total 70 - 160%; Females, age >=50 yrs: Free 65 - 160%, Total 80 - 160%.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Lipemic or cloudy specimens may lead to an underestimation of the total Protein S Antigen level. The presence of rheumatoid factor may lead to an overestimation of the total Protein S Antigen level.

Test Details

Days Test Performed

Monday - Friday

Analytic Time

2 - 5 days

Soft Order Code

PSTF

MiChart Code

Protein S, Total and Free

Synonyms

Synonyms

Protein S Antigen, Free and Total
PROTEIN S ANTIGEN, PLASMA
PSF
PST
PROTEIN S ANTIGEN, FREE
PROTEIN S ANTIGEN, TOTAL

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Laboratory

Sendout

Laboratory Reference

Mayo PSTF (83049)

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 3 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a polypropylene plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.

Contraindication

This test is not indicated in patients receiving coumadin therapy.

Container

Blue Top Tube

Normal Volume

1 mL plasma

Minimum Volume

0.5 mL plasma

Additional Information

If the Free Protein S Antigen level is abnormal, Total Protein S Antigen (PST) (MML 80994) will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test is sent to Mayo Medical Laboratories.

Billing Information

Fee Codes


CPT Code

85306

Reflex Fee Code

20164

LOINC

Z238-6

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