Test Overview
Test Methodology

High Resolution Agarose Electrophoresis

Test Usage

Used to differentiate between normal renal function, glomerular proteinuria and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Severe glomerular basement membrane damage will result in large amounts of polyclonal gammaglobulins being lost in the urine. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight proteins.

Reference Range *

Pathologist interpretation of results provided.

Test Details
Days Set Up
Varies; test performed once per week
Analytic Time

24 hours

Soft Order Code
UPE
MiChart Code
Urine Protein Electrophoresis
Synonyms
  • Electrophoresis, Protein, Urine
  • Globulins, Urine
  • UPE
  • Urine Electrophoresis
  • Urine Protein Electrophoresis
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Preservative-free urine, first AM void preferred (24 hour urine or random urine acceptable). Refrigerate up to 1 week.

Rejection Criteria
Specimens collected with Acid Preservative are not acceptable.
Normal Volume
10 mL urine
Minimum Volume
5 mL urine
Additional Information

Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. In order to provide accurate interpretation, abnormal results will be followed by Bence Jones Protein Screen (urine immunofixation) at an additional charge, if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

Billing
CPT Code
84166
Fee Code
21993
Pro Fee CPT
84166-26
Pro Fee Code
84166.4
NY State Approved
No