Test Overview
Test Methodology

Capillary Electrophoresis

Test Usage

Serum protein electrophoresis is an evaluation for monoclonal gammopathies, Waldenstrom's macroglobulinemia, multiple myeloma, liver disease, inflammatory states, nephrotic syndrome, amyloidosis and A1AT deficiency disease. Also used for evaluation for low back pain, arthritis, lymphoma, leukemia and anemia. The small bands and minor alterations detected will have different significance depending on the clinical situation.

Reference Range *

Total Protein (age >=12yrs): 6.0 - 8.3 g/dL; Albumin: 3.43 - 4.84 g/dL, Alpha-1 Globulin: 0.21 - 0.44 g/dL, Alpha-2 Globulin: 0.54 - 0.97 g/dL, Beta Globulin: 0.65 - 1.03 g/dL, Gamma Globulin: 0.70 - 1.47 g/dL, Albumin/Globulin Ratio: 0.88 - 2.30. Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

24 hours

Soft Order Code
TPE
MiChart Code
Protein Electrophoresis, Serum
Synonyms
  • Electrophoresis, Protein, Serum
  • High Resolution Electrophoresis, Serum
  • Serum Protein Electrophoresis
  • SPEP
  • PROTEIN ELECTROPHORESIS
  • ALB/GLOB
  • ALBUMIN
  • ALPHA 1
  • ALPHA 2
  • BETA
  • GAMMA
  • T PROTEIN
  • TPINTERP
  • ALPHA-1
  • ALPHA-2
  • BETA-GLOBULIN
  • GAMMA GLOBULIN
  • TOTAL PROTEIN
  • PROTEIN ELECTROPHORESIS INTERP
  • ALBUMIN RESULT
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. If cryoglobulin is suspected, the specimen must be drawn in a red top tube and maintained at 37 degrees C.

Alternate Specimen
Red top tube.
Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.4 mL serum
Additional Information

Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. In order to provide accurate interpretation, abnormal results will be followed by serum immunoglobulins and serum immunofixation at an additional charge, and by immunoglobulin free light chains and/or immunoglobulin G subclass 4 at an additional charge, if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

Billing
CPT Code
84165
Fee Code
30951
Pro Fee CPT
84165-26
Pro Fee Code
84165
Resources