Update Type: Test Resumed
Test Updated: 02/21/2024
Test Overview
Test Methodology

Radioimmunoassay (RIA)

Test Usage

An aid in monitoring antiresorptive and anabolic therapy in patients with osteoporosis. An adjunct in the assessment of conditions associated with increased bone turnover such as Paget disease. Procollagen I Intact N-terminal (PINP) values should not be used as a screening test for osteoporosis in the general population.

Reference Range *

Reference values have not been established for patients who are less than 18 years of age. Adult male: 22 - 87 mcg/L; Adult female premenopausal: 19 - 83 mcg/L; Adult female post menopausal: 16 - 96 mcg/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday
Analytic Time

2 - 6 days

Soft Order Code
MiChart Code
Procollagen Type 1 Intact N-terminal Propeptide (P1NP), (MAYO-FPNTS)
Reference Laboratory
Mayo PINP (61695)
Special Testing
Specimen Requirements

This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. Collect blood in red top tube (SST is acceptable). Centrifuge, aliquot serum into a plastic vial, and freeze (preferred) or refrigerate.

Alternate Specimen
SST acceptable.
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
Storage Temperature
Refrigerated 7 days, Frozen 14 days.
Additional Information

Test sent to Mayo Medical Laboratories.

CPT Code
Fee Code