Test Overview
Test Methodology

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection

Test Usage

This test is preferred test during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. The random urine collection for this test allows for the diagnosis to be established and treatment to be initiated quickly.

Reference Range *

UROPORPHYRINS, OCTA: < or =30 nmol/L
HEPTACARBOXYLPORPHYRINS: < or =7 nmol/L
HEXACARBOXYLPORPHYRINS: < or =2 nmol/L
PENTACARBOXYLPORPHYRINS: < or =5 nmol/L
COPROPORPHYRINS, TETRA: < or =110 nmol/L
PORPHOBILINOGEN: < or =1.3 mcmol/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

3 - 5 days

Soft Order Code
PQNRU
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo PQNRU
    Section
    Special Testing
    Specimen Requirements
    Collection Instructions

    Collect specimen in a clean container (wrap in foil if cannot be transferred to amber bottle in a short period of time). Transfer to an amber bottle to protect the specimen from light as soon as possible. Send urine to Specimen Processing frozen.

    Special Handling

    Protect from light and strict frozen. Patient should abstain from alcohol for 24 hours before collection

    Normal Volume
    50 mL urine
    Minimum Volume
    15 mL urine
    Storage Temperature
    Frozen
    Rejection Criteria
    Not protected from light or frozen
    Additional Information

    Test performed by Mayo Clinic Laboratories

    Billing
    CPT Code
    84110, 84120
    NY State Approved
    No