Test Overview
Test Methodology

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection

Test Usage

This test is preferred test during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. The random urine collection for this test allows for the diagnosis to be established and treatment to be initiated quickly.

Reference Range *

UROPORPHYRINS, OCTA: < or =30 nmol/L
HEPTACARBOXYLPORPHYRINS: < or =7 nmol/L
HEXACARBOXYLPORPHYRINS: < or =2 nmol/L
PENTACARBOXYLPORPHYRINS: < or =5 nmol/L
COPROPORPHYRINS, TETRA: < or =110 nmol/L
PORPHOBILINOGEN: < or =1.3 mcmol/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

3 - 5 days

Soft Order Code
PQNRU
Laboratory
Sendout
Reference Laboratory
Mayo PQNRU
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a clean container (wrap in foil if cannot be transferred to amber bottle in a short period of time). Transfer to an amber bottle to protect the specimen from light as soon as possible. Send urine to Specimen Processing frozen.

Special Handling

Protect from light and strict frozen. Patient should abstain from alcohol for 24 hours before collection

Normal Volume
50 mL urine
Minimum Volume
15 mL urine
Storage Temperature
Frozen
Rejection Criteria
Not protected from light or frozen
Additional Information

Test performed by Mayo Clinic Laboratories

Billing
CPT Code
84110, 84120