Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis

Test Usage

Biochemical diagnosis of acute, neurologic porphyrias, including actute intermittent porphyria (AIP), hereditary coproporphyria (HCP), and variegate porphyria (VP).

Reference Range *

< or = 1.3 mcmol/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

2 - 6 days

Soft Order Code
PBG
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo PBGU (82068)
    Section
    Special Testing
    Specimen Requirements
    Collection Instructions

    Collect random urine specimen. Freeze. Protect specimen from light.

    Special Handling

    Protect specimen from light.

    Normal Volume
    20 mL urine
    Minimum Volume
    15 mL urine
    Additional Information

    Increased urinary PBG excretion in the presence of suggestive clinical symptoms is consistent with a biochemical diagnosis of actute porphyrias. A diagnosis of AIP can be confirmed by measurement of PBG deaminase activity. HCP and VP can be confirmed by measurement of fecal porphyrins. Test sent to Mayo Medical Laboratories.

    Billing
    CPT Code
    84110
    Fee Code
    22039
    LOINC
    13797-6
    NY State Approved
    No