Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis

Test Usage

Biochemical diagnosis of acute, neurologic porphyrias, including actute intermittent porphyria (AIP), hereditary coproporphyria (HCP), and variegate porphyria (VP).

Reference Range *

< or = 1.3 mcmol/L

Test Details
Days Set Up
Monday - Friday
Analytic Time

2 - 6 days

Soft Order Code
PBG
MiChart Code
Pbg Deaminase, RBCs
Synonyms
  • PBG
  • Porphobilinogen, QN, Random, U
Laboratory
Sendout
Reference Laboratory
Mayo PBGU (82068)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect random urine specimen. Freeze. Protect specimen from light.

Special Handling

Protect specimen from light.

Normal Volume
20 mL urine
Minimum Volume
15 mL urine
Additional Information

Increased urinary PBG excretion in the presence of suggestive clinical symptoms is consistent with a biochemical diagnosis of actute porphyrias. A diagnosis of AIP can be confirmed by measurement of PBG deaminase activity. HCP and VP can be confirmed by measurement of fecal porphyrins. Test sent to Mayo Medical Laboratories.

Billing
CPT Code
84110
Fee Code
22039
LOINC
13797-6
NY State Approved
No