Test Overview
Test Methodology

Enzymatic End point/Spectrofluorometric

Test Usage

Confirmation of a diagnosis of acute intermittent porphyria (AIP).

Reference Range *

> or = 7.0 nmol/L sec; 6.0 - 6.9 nmol/L sec (indeterminate); <6.0 nmol/L/sec (diminished). Reference ranges have not been established for patients who are <16 years of age.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Tuesday, Thursday
Analytic Time

4 - 10 days

Soft Order Code
MiChart Code
Porphobilinogen Deaminase, Erythrocytes
  • PBG Deaminase, RBC
  • Porphobilinogen Deaminase (PBG-D), RBC
  • PBG Deaminase, BLOOD
Reference Laboratory
Mayo PBGD_ (88925)
Special Testing
Specimen Requirements
Collection Instructions

Patient should abstain from alcohol for 24 hours and be off medications for 1 week prior to specimen collection. If it is clinically inappropriate to discontinue medications, forward a list of medications with the specimen. Collect blood in a green top tube from a fasting patient (12 - 14 hour fast). Place on wet ice immediately. Refrigerate and send intact whole blood within 24 hours of collection.

Special Handling

Fasting specimen. Place on wet ice immediately.

Alternate Specimen
EDTA lavender top tube
Normal Volume
5 mL whole blood
Minimum Volume
3 mL whole blood
Storage Temperature
Refrigerated preferred, ambient acceptable
Additional Information

Test sent to Mayo Medical Laboratories.

CPT Code
Fee Code