Performed at authorized locations by point of care operators. Bilirubin is a waste product derived from the breakdown of hemoglobin. Increased red cell destruction or defective bilirubin conjugation by the liver , will increase the amount of bilirubin in the body. If the bilirubin concentration is high enough, pigment will accumulate in the tissues producing jaundice. Jaundice may be due to diseases of blood, liver, bile ducts, or pancreas. In newborns kernicterus or hemolytic disease of the newborn could be a potential cause.

The POC total bilirubin test is performed to detect high levels of bilirubin, particularly in neonates. If warranted, based on the age of the infant and POC total bilirubin level, an indirect and direct bilirubin will be automatically reflexed.