CoaguChek- clotting (recombinant thromboplastin)
Performed at authorized locations by point of care operators. Prothrombin time and INR are monitored in the point of care for patients taking oral anticoagulants, which allow physicians to adjust medications levels to the prescribed therapeutic or target range.
Reference ranges are available in the Coaguchek XS System test procedure located on the POC website: https://www.pathology.med.umich.edu/point-of-care
•When a patient is on IV therapy, do not collect the blood sample from the same arm receiving the infusion line.
•Results are unaffected by heparin concentrations up to 0.8 U/mL
•Testing is insensitive to low molecular weight heparin (LMWH) up to 2 IU anti-factor Xa activity/mL
•The presence of anti-phospholipid antibodies (APAs) can potentially lead to prolonged clotting times i.e. elevated INR values.
•Samples of patients treated with protamine sulfate cannot be tested with this system.
•The results obtained cannot be used for the determination or the assessment of a therapy with factor II or factor X antagonists.
Dependent on patient's coagulation status, results are obtained in less than 2 minutes.
Fingerstick: Use first drop, avoid excessive squeezing or milking.