Flow Cytometric Immunophenotyping
Screening or confirming the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH). See http://www.pathology.med.umich.edu/handbook/Tables/Flow_Cytometry_Panel… for all Flow Cytometry Panels.
RED BLOOD CELLS:
PNH RBC-Partial Antigen loss: 0.00-0.99%
PNH RBC-Complete Antigen loss: 0.00-0.01%
PNH Granulocytes: 0.00-0.01%
PNH Monocytes: 0.00-0.05%
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Requires an adequate number of viable cells for analysis. Improper collection or transport may result in decreased cell viability and cancellation of testing.
1 - 2 days
- INULIN TEST FOR PNH
- Acid Hemolysin
- GPI-Linked Antigens
- Ham's Test
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Panel 8: Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Pi-Linked Antigen, Blood
- PNH MARKER PANEL
- Hams Test
- PNH Marker Panel Shadow
The following information is required on a Hematopathology Consult requisition:
[list order =Y]
Relevant clinical history
Clinical or morphological findings and suspicions
Date and time of collection
Phone number and after hours pager number for ordering physician
Collect blood in a yellow top ACD solution A or B Vacutainer® tube.<li>
Send intact specimen at room temperature within 12 hours of collection.<li>
Do not refrigerate or freeze.
Test includes WBC panel (CD14, CD15, CD16, CD24, CD33, CD45, FLAER) and RBC panel (CD235a, CD59). Test performed by Mayo Clinic Laboratories.