Test Overview
Flow Cytometric Immunophenotyping
Screening or confirming the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH). See http://www.pathology.med.umich.edu/handbook/Tables/Flow_Cytometry_Panel… for all Flow Cytometry Panels.
RED BLOOD CELLS:
PNH RBC-Partial Antigen loss: 0.00-0.99%
PNH RBC-Complete Antigen loss: 0.00-0.01%
PNH Granulocytes: 0.00-0.01%
PNH Monocytes: 0.00-0.05%
Requires an adequate number of viable cells for analysis. Improper collection or transport may result in decreased cell viability and cancellation of testing.
Test Details
1 - 2 days
- INULIN TEST FOR PNH
- Acid Hemolysin
- GPI-Linked Antigens
- Ham's Test
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- CD14
- CD24
- FLAER
- PNH
- INULIN
- Panel 8: Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Pi-Linked Antigen, Blood
- PNH MARKER PANEL
- CD33
- CD45
- CD59
- Hams Test
- PNHS
- PNH Marker Panel Shadow
Specimen Requirements
The following information is required on a Hematopathology Consult requisition:
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Relevant clinical history
Clinical or morphological findings and suspicions
Date and time of collection
Phone number and after hours pager number for ordering physician
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Collect blood in a yellow top ACD solution A or B Vacutainer® tube.<li>
Send intact specimen at room temperature within 12 hours of collection.<li>
Do not refrigerate or freeze.
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Additional Information
Test includes WBC panel (CD14, CD15, CD16, CD24, CD33, CD45, FLAER) and RBC panel (CD235a, CD59). Test performed by Mayo Clinic Laboratories.