Evaluation by the blood bank house officers to determine if further testing should be performed to determine immune-based platelet refractoriness.
Platelet refractoriness evaluation should be ordered on patients who show consistent failure to respond to transfused platelets and in whom significant non-immune causes of platelet refractoriness have been excluded. If the initial evaluation is suggestive of immune refractoriness, the care team will be contacted to draw 2 pink-top tubes for further evaluation of platelet refractoriness by platelet cross-match with random donors performed at the Red Cross in Detroit. If the cross-match evaluation shows a high degree of immune refractoriness, the patient’s previously drawn blood will be evaluated for anti-HLA antibodies. If this evaluation shows a high degree of anti-HLA antibodies, then HLA-matched platelets will be ordered for the patient.
Not platelet refractory, non-immune platelet refractory, or suspicious for immune platelet refractory.
- PLT CONS
- Platelet Refractory Consult
- Platelet Refractoriness Evaluation
This test is available only for University of Michigan registered patients.
Please refer to Platelet Refractoriness Evaluation Supplemental Information available online at http://www.pathology.med.umich.edu/handbook/Tables/Platelet_Refractorin… for additional information.