Days Set Up
Monday - Friday
Analytic Time

1 day

Soft Order Code

Test Updated:


Platelet Refractory Consult
Platelet Refractoriness Evaluation

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Test Overview

Test Methodology

Evaluation by the blood bank house officers to determine if further testing should be performed to determine immune-based platelet refractoriness.

Test Usage

Platelet refractoriness evaluation should be ordered on patients who show consistent failure to respond to transfused platelets and in whom significant non-immune causes of platelet refractoriness have been excluded. If the initial evaluation is suggestive of immune refractoriness, the care team will be contacted to draw 2 pink-top tubes for further evaluation of platelet refractoriness by platelet cross-match with random donors performed at the Red Cross in Detroit. If the cross-match evaluation shows a high degree of immune refractoriness, the patient’s previously drawn blood will be evaluated for anti-HLA antibodies. If this evaluation shows a high degree of anti-HLA antibodies, then HLA-matched platelets will be ordered for the patient.

Reference Range

Not platelet refractory, non-immune platelet refractory, or suspicious for immune platelet refractory.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

This test is available only for University of Michigan registered patients.

Pink Top Tube
Minimum Volume

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.