Test Overview
Test Methodology

Optical turbidometric aggregation and ATP release using a Lumi-Aggregometer.

Test Usage

Evaluation of functional integrity of the platelets, aid in diagnosis of von Willebrand's disease, Glanzmann's thrombasthenia, storage pool disease, Bernard-Soulier syndrome, and platelet function abnormalities induced by metabolic abnormalities.

Reference Range *

Interpretative report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Tuesday, Wednesday, Thursday
Analytic Time

4 hours

Soft Order Code
AGG
MiChart Code
AGGLUTINATING AB
Synonyms
  • Platelet function with EPI
  • Platelet function with ADP
  • Platelet function with epinephrine (EPI)
  • Platelet Function Studies
  • Ristocetin Induced Platelet Agglutination
  • Ristocetin Aggregation
Laboratory
Hematopathology
Section
Coagulation
Specimen Requirements
Collection Instructions

Contact MLabs Client Services Center at 800-862-7284 for information regarding scheduling the test. The patient must have specimen collected at the UM Cardiovascular Center blood draw station level 3 or C.S. Mott Children's Hospital and Von Voigtlander Women's Hospital blood draw station.

Special Handling
  • DO NOT DRAW PATIENT WITHOUT SPECIAL COAGULATION TECHNOLOGIST PRESENT.
    DO NOT SEND THROUGH PNEUMATIC TUBE SYSTEM.
Contraindications
Test is contraindicated in:
<ul><li>
Patients with platelet counts less than 140,000/ml.<li>Requires medical director approval.<li>
Patients taking medications known to adversely affect platelet function.<li>These drugs, including aspirin and medications containing aspirin, other NSAIDs, anti-depressants and a variety of other drugs need to be held for 10 days prior to the scheduled test.
Children under 2 years of age.
</ul>
Normal Volume
<ul><li>
10 full 2.8ml 3.2% sodium citrate blue top Vacutainer® tubes
1 2ml EDTA K2 lavender top Vacutainer® tube
</ul>
Minimum Volume
<ul><li>
4 full 2.8ml 3.2% sodium citrate blue top Vacutainer® tubes
1 2ml EDTA K2 lavender top Vacutainer® tube
</ul>
Additional Information

Congenital platelet function abnormalities are rare. Many acquired conditions can interfere with normal platelet function. Aspirin is among the most common responsible agents, but many other drugs may alter platelet function. Patients with uremia, severe liver disease, or advanced alcohol-related conditions often develop a complex bleeding diathesis that induces platelet dysfunction. Myeloproliferative disorders and dysproteinemias may exhibit similar problems.

Billing
CPT Code
85576
Fee Code
31132
NY State Approved
No