Test Overview
Optical turbidometric aggregation and ATP release using a Lumi-Aggregometer.
Evaluation of functional integrity of the platelets, aid in diagnosis of von Willebrand's disease, Glanzmann's thrombasthenia, storage pool disease, Bernard-Soulier syndrome, and platelet function abnormalities induced by metabolic abnormalities.
Interpretative report provided.
Test Details
4 hours
- Platelet function with EPI
- Platelet function with ADP
- Platelet function with epinephrine (EPI)
- Platelet function with Eppy
- Platelet Function Studies
- AGG
- PLATELET AGGREGATION STUDIES
- Ristocetin Induced Platelet Agglutination
- Ristocetin Aggregation
Specimen Requirements
Contact MLabs Client Services Center at 800-862-7284 for information regarding scheduling the test. The patient must have specimen collected at the UM Cardiovascular Center blood draw station level 3 or C.S. Mott Children's Hospital and Von Voigtlander Women's Hospital blood draw station.
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DO NOT DRAW PATIENT WITHOUT SPECIAL COAGULATION TECHNOLOGIST PRESENT.
DO NOT SEND THROUGH PNEUMATIC TUBE SYSTEM.
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Patients with platelet counts less than 140,000/ml.<li>Requires medical director approval.<li>
Patients taking medications known to adversely affect platelet function.<li>These drugs, including aspirin and medications containing aspirin, other NSAIDs, anti-depressants and a variety of other drugs need to be held for 10 days prior to the scheduled test.
Children under 2 years of age.
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4 full 2.8 ml 3.2% sodium citrate blue top Vacutainer® tubes
1 2 ml EDTA K2 lavender top Vacutainer® tube
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4 full 2.8 ml 3.2% sodium citrate blue top Vacutainer® tubes
1 2 ml EDTA K2 lavender top Vacutainer® tube
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Additional Information
Congenital platelet function abnormalities are rare. Many acquired conditions can interfere with normal platelet function. Aspirin is among the most common responsible agents, but many other drugs may alter platelet function. Patients with uremia, severe liver disease, or advanced alcohol-related conditions often develop a complex bleeding diathesis that induces platelet dysfunction. Myeloproliferative disorders and dysproteinemias may exhibit similar problems.