Test Overview
Test Methodology


Test Usage

Deep vein thrombosis (DVT) and coronary artery disease (CAD) are associated with increased PAI-1 levels. Elevated PAI-1 levels may help predict risk of reinfarction in survivors of myocardial infarction, particularly in young individuals. PAI-1 levels tend to be higher in individuals with the 4G/4G genotype.

Reference Range *

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Genetic testing by PCR provides exceptionally high sensitivity and specificity. Incorrect genotyping results can be caused by rare polymorphisms in primer binding sites. This assay analyzes only the PAI 4G/5G locus and does not measure genetic abnormalities elsewhere in the genome.

Test Details
Days Set Up
Wednesday, Saturday
Analytic Time

6 - 14 days

Soft Order Code
  • PAI-1 Locus 4G/5G
  • 4G/5G Genotyping
  • PAI-1 Polymorphism
Reference Laboratory
Mayo FPAIG (Esoterix Coagulation 129100)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a lavender top or a yellow top (ACD) tube. Refrigerate and send intact specimen.

Alternate Specimen
Lavender EDTA tube is preferred, ACD (yellow top) is acceptable
Normal Volume
5 mL EDTA or ACD whole blood
Minimum Volume
1 mL EDTA or ACD whole blood
Additional Information

Test sent to Mayo Medical Laboratories, performed by Esoterix Coagulation.

CPT Code
Fee Code