Enzyme-Linked Immunosorbent Assay (ELISA)
IgA cardiolipin antibody is occasionally detected in SLE and SLE-like patients and appears to be most commonly associated with cerebrovascular thrombosis.
<15 APL (negative), 15.0 – 39.9 APL (weakly positive), 40.0 – 79.9 APL (positive), > or =80.0 APL (strongly positive). APL refers to IgA Phospholipid Units. One APL unitis 1 microgram of IgA antibody.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
The immunoassay for phospholipid antibodies does not distinguish between autoantibodies and antibodies produced in response to infectious agents or as epiphenomena following thrombosis. For this reason, a single positive test result is not sufficient to meet accepted serologic criteria for the diagnosis of APS.
4 - 6 days
- Phospholipid (Cardiolipin) Antibody IgA
- IgA Phospholipid Antibody (APL)
- aCL Antibody
Collect specimen in an SST or red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Test sent to Mayo Medical Laboratories.