Enzyme-Linked Immunosorbent Assay (ELISA)
IgA cardiolipin antibody is occasionally detected in SLE and SLE-like patients and appears to be most commonly associated with cerebrovascular thrombosis.
<15 APL (negative), 15.0 – 39.9 APL (weakly positive), 40.0 – 79.9 APL (positive), > or =80.0 APL (strongly positive). APL refers to IgA Phospholipid Units. One APL unitis 1 microgram of IgA antibody.
The immunoassay for phospholipid antibodies does not distinguish between autoantibodies and antibodies produced in response to infectious agents or as epiphenomena following thrombosis. For this reason, a single positive test result is not sufficient to meet accepted serologic criteria for the diagnosis of APS.
4 - 6 days
- Phospholipid (Cardiolipin) Antibody IgA
- IgA Phospholipid Antibody (APL)
- aCL Antibody
Collect specimen in an SST or red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Test sent to Mayo Medical Laboratories.