Anti-parietal Cell Antibody
PARIETAL CELL ANTIBODY
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Indirect Fluorescent Antibody (IFA), Mouse stomach kidney substrate.
Useful in the diagnosis of pernicious anemia in which approximately 80% of patients demonstrate antibodies. A positive test in the presence of a megaloblastic anemia makes pernicious anemia a probable diagnosis. A negative test will help differentiate pernicious anemia from other anemias and Whipple's disease. Rarely, antiparietal cell antibodies are found in patients with gastric ulcer, atrophic gastritis, chronic thyroiditis, iron deficiency anemia, juvenile diabetes mellitus, idiopathic Addison's disease, gastric carcinoma, and in the normal population.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.