Days Set Up
Tuesday, Friday
Analytic Time

8 hours

MiChart Code
Anti-Parietal Antibody
Soft Order Code
PAC

Test Updated:

Synonyms

Anti-parietal Cell Antibody
PAC
PARIETAL CELL ANTIBODY

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Indirect Fluorescent Antibody (IFA), Mouse stomach kidney substrate.

Test Usage

Useful in the diagnosis of pernicious anemia in which approximately 80% of patients demonstrate antibodies. A positive test in the presence of a megaloblastic anemia makes pernicious anemia a probable diagnosis. A negative test will help differentiate pernicious anemia from other anemias and Whipple's disease. Rarely, antiparietal cell antibodies are found in patients with gastric ulcer, atrophic gastritis, chronic thyroiditis, iron deficiency anemia, juvenile diabetes mellitus, idiopathic Addison's disease, gastric carcinoma, and in the normal population.

Reference Range

Negative

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate for up to 3 days.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.2 mL serum

Billing Information

CPT Code
86256
Pro Fee Code
 
Insurance Auth Info
 
LOINC
5271-2

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.